Agent is Unreachable (REASON = The agent is running but is currently not ready to accept client requests).

1.) Stop the agent:
emctl stop agent

2.) Set the following properties as shown below:
emctl setproperty agent -allow_new -name MaxInComingConnections -value 150
emctl setproperty agent -allow_new -name _cancelThread  -value 210

3.) Take backup and edit AGENT_INST/sysman/config/emd.properties

Change MaxThreads value to 250

Default
MaxThreads=10

to
MaxThreads=250

4.) Start the agent:
emctl start agent